B.Sc., HKBU; Ph.D., HKU
Professor and Head of Deparment of Biology,
Director of Croucher Institute for Environmental Sciences,
Hong Kong Baptist University
Rm. T704A; (852) 3411-7053
CURRENT RESEARCH INTERESTS
MAJOR EXTERNAL RESEARCH GRANTS (PRINCIPAL INVESTIGATOR)
Molecular Endocrinology and Physiology
BHY Yeung and Chris KC Wong (2011) Stanniocalcin-1 regulates re-epithelialization in human keratinocytes. PLoS One (in press).
WKF Tse, SC Chow, KP Lai, DWT Au and Chris KC Wong (2011) Modulation of ion transporter expression in gill mitochondrion-rich cells of eels acclimated at low- Na+ or Cl- freshwater. J Exp Zool A Ecol Genet and Physiol 315(7):385-393.
SC Chow and Chris KC Wong (2011) The regulatory functions of hyperosmotic stress-induced signaling cascades to the expressions of osmotic stress transcriptional factors and osmolyte transporters in primary gill cell culture of freshwater Japanese eels. J Exp Biol 214:1264-1270.
AYS Law, BHY Yeung, LY Ching and Chris KC Wong (2011) Sp1 is a transcription repressor to stanniocalcin-1 expression in TSA-treated human colon cancer cells, HT29. J Cell Biochem 112:2089-2096.
AYS Law, Chris KC Wong (2010) Stanniocalcin-2 Promotes Epithelial Mesenchymal Transition and Metastasis in Hypoxic Human Ovarian Cancer Cells. Exp Cell Res 316:3425-3434.
AYS Law and Chris K.C. Wong (2010) Stanniocalcin-2 is a HIF-1 target gene that promotes cell proliferation in hypoxia. Exp Cell Res 316:466-476.
AYS Law, LY Ching, KP Lai and Chris K.C. Wong (2010) Identification and characterization of the hypoxia-responsive element in human stanniocalcin-1 gene. Mol Cell Endocrinol. 314: 118-127.
SC Chow, LY Ching, AMF Wong and Chris KC Wong (2009) The cloning and the regulation of Na+-Cl--taurine transporter expression in gill cells of freshwater Japanese eels. J Exp Biol. 212:3205-3210.
AYS Law, KP Lai, WC Lui, and Chris KC Wong (2008) Histone deacetylase inhibitors induced-cellular apoptosis involves stanniocalcin-1 activation. Exp Cell Res 314:2975-2984.
AYS Law, KP Lai, CKM Ip, AST Wong, GF Wagner, and Chris KC Wong (2008) Epigenetic and HIF-1 Regulation of Stanniocalcin-2 Expression in Human Cancer Cells. Exp Cell Res 314:1823-1830.
Environmental and Molecular Toxicology
AYS Law, X Wei, XW Zhang, NK Mak, KC Cheung, MH Wong, J Giesy and Chris KC Wong (2011) Biological analysis of endocrine-disrupting chemicals in animal meats from the Pearl River Delta, China. J Expo Sci Environ Epidemiol (in press).
YG Zhao, HT Wan, AYS Law, X Wei, YQ Huang, J Giesy, MH Wong and Chris KC Wong (2011) Risk Assessment for human consumption of perfluorinated compound-contaminated freshwater and marine fish from Hong Kong and Xiamen. Chemosphere (in press).
BHY Yeung, HT Wan, AYS Law and Chris KC Wong (2011) Endocrine disrupting chemicals: multiple effects on testicular signaling and spermatogenesis. Spermatogenesis 1(3):231-239 (Review article).
X Wei, YQ Huang, MH Wong, JP Giesy and Chris KC Wong (2011) Assessment of risk to humans of bisphenol A in marine and freshwater fish from Pearl River Delta, China. Chemosphere 85:122-128.
X Zhang, H Chang, S Wiseman, Y He, E Higley, P Jones, Chris KC Wong, A Al-Khedhairy, J Giesy and M Hecker (2011) Bisphenol A disrupts steroidogenesis in human H295R cells. Toxicol Sci 121:320-327.
HT Wan, YG Zhao, MH Wong, CKF Lee, WSB Yeung, JP Giesy and Chris KC Wong (2011) Testicular signaling is the potential target of PFOS-mediated subfertility in male mice. Biol Reprod 84:1016-1023.
X Wei, CKF Lee, WSB Yeung, John P Giesy, MH Wong, XW Zhang, M Hecker and Chris KC Wong (2011) Effect of Perinatal and Postnatal Bisphenol A Exposure to the Regulatory Circuits at the hypothalamus-pituitary-gonadal axis of CD-1 Mice. Reproductive Toxicol 31:409-417.
HS Wang, J Du, KL Ho, HM Leung, MH Lam, JP Giesy, Chris KC Wong* and MH Wong* (2011) Exposure of Hong Kong residents to PBDEs and their structure analogues through market fish consumption. J Hazard Mater 192(1):374-380.
AO Leung, J Zheng, CK Yu, WK Liu, Chris KC Wong, ZW Cai and MH Wong (2011) Polybrominated diphenyl ethers and polychlorinated dibenzo-p-dioxins and dibenzofurans in surface dust at an E-waste processing site in southeast China. Environ Sci Technol 45(13):5775-5782.
X Wei, LY Ching, SH Cheng, MH Wong, Chris KC Wong (2010) The detection of dioxin- and estrogenic-like pollutants in marine and freshwater fishes cultivated in Pearl River Delta, China. Environ Pollution 158:2302-2309.